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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3537fc03eae70ec1de2c4c930ee7a8cb784f51d5389f40da0ee0bc6e14b2d5f' 
  AND token = '+GfPoMSLpobJoWFiF7e/qL0Xvf6nGV1emoJA69EPoN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}